TITLE:
Possibilities of transcatheter treatment of patients after extensive ischemic stroke
AUTHORS:
Ivan V. Maksimovich
KEYWORDS:
Extensive Ischemic Stroke; Neurological Deficits; Post-Stroke Dementia; Transcatheter Treatment; Laser Revascularization
JOURNAL NAME:
World Journal of Neuroscience,
Vol.3 No.3,
July
22,
2013
ABSTRACT:
The research investigates the efficacy of brain transcatheter
laser revascularization in patients who have had extensive ischemic stroke.
1125 patients aged 29 - 81 (average age 75) with cerebral atherosclerosis were examined. The examination plan included: CT brain scan, magnetic resonance
imaging (MRI), brain scintigraphy (SG), rheoencephalography (REG), cerebral
multi-gated angiography (MUGA), laboratory tests, assessment of severity of
dementia (CDR), cognitive impairment (MMSE) and activities of daily living
(IB). 93 patients suffered extensive
ischemic stroke of whom 7 (7.53%) had 10 - 15 IB points, 25 (26.88%)—20 -
30 IB points, 61 (65.59%)—35 - 45 IB points. 69 patients underwent transcatheter
treatment (Test Group). 24 patients underwent conservative treatment (Control
Group). High-energy laser systems were used for revascularization of major
intracranial arteries; lowenergy laser systems were used for revascularization of distal intracranial branches. Test Group: 67 (97.10%) patients had good immediate angiographic outcome manifested in the
restoration of lumen and patency of the affected vessels as well as in
collateral revascularization. 12 - 24 months later the following positive trend
was observed: 14 (20.59%) patients demonstrated
good clinical outcome (IB 90 - 100); 26 (38.24%) patients had
satisfactory clinical outcome (IB 75 - 85); 28 (41.18%) patients showed
relatively satisfactory clinical outcome (IB 60 - 70); relatively positive clinical
outcome (IB satisfactory clinical
outcome (IB 60 - 70), relatively positive clinical outcome (IB causes regression of
mental, intellectual and motor disorders, promotes regression of post-stroke
dementia and significantly improves the
quality of life, which makes it noticeably different from the conservative
methods of treatment.