TITLE:
Retrospective study of MRI images to examine the effects of estrogen supplementation on breast tissue: A pilot study in Asian Taiwan
AUTHORS:
Ting-Kai Leung, Pai-Jung Huang, Chih-Hsiung Wu, Chi-Ming Lee, Chin-Sheng Hung, Hung-Hua Liang, Jeng-Fong Chiou
KEYWORDS:
Breast MRI; Estrogen; Hormone Effect; Phytoestrogen; Proliferative Breast Glandular Tissue
JOURNAL NAME:
Health,
Vol.5 No.7D,
July
18,
2013
ABSTRACT:
MRI provides a highly
sensitive technique for early detection of abnormal breast tissue. It is useful
for identifying a status of proliferation, angiogenesis, and microvascular
permeability, which may indicate early breast neoplasm formation. We
retrospectively studied 2005 breast MRI images from Taiwanese women and classified them as either healthy or unhealthy according to BI-RADS categories. A
subgroup of our study patients had received
estrogen supplements, containing estrogen components or phytoestrogen, for at least 3 months. These patients’ images were also classified into the healthy and unhealthy groups. These two
groups were compared and a significant difference was found between them (P