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V. Alagarsamy, S. Meena, K. V. Ramseshu, V. R. Solomon, K. Thirumurugan, K. Dhanabal and M. Murugan, “Synthesis, Analgesic, Anti-Inflammatory, Ulcerogenic Index and Antibacterial Activities of Novel 2-Methylthio3-substituted-5,6,7,8-tetrahydrobenzo(b)thieno[2,3-d]pyrimidin-4(3H)-ones,” European Journal of Medicinal Chemistry, Vol. 41, No. 11, 2006, pp. 1293-1300.
has been cited by the following article:
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TITLE:
Design, Synthesis and Pharmacological Evaluation of New Nonsteroidal Anti-Inflammatory Derived from 3-Aminobenzothieno[2,3-d]pyrimidines
AUTHORS:
Hend Nagah Hafez, Omar Khalid Al-Duaij, Abdel-Rhman Barakat A. El-Gazzar
KEYWORDS:
Spirobenzothienopyrimidine; Triazolopyrimidine; Pyrazolopyrimidine; Analgesic; Anti-inflammatory; Ulcerogenic Effect
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.3 No.2,
June
13,
2013
ABSTRACT:
During the
last few years, condensed thienopyrimidine derivatives have received
considerable attention. The therapeutic importance of thienopyrimidines
prompted us to synthesize some of spiro(benzothieno[2,3-d]pyrimidine-4-one) derivatives. Some of the novel benzothino-pyrimidine
derivatives 3a, 9b,
10b, 11a, 11b, and 11c showed considerable potent
anti-inflammatory and analgesic activity of superior G.I.T. safety profile in
experimental rats in comparing to indomethacin and tramadol as reference drugs.