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has been cited by the following article:

• TITLE: Advanced Breast Angiosarcoma Completely Responding to Chemotherapy

  AUTHORS: Zhiguo Luo, Qian Wang, Wei Peng, Jianhua Chang, Xichun Hu, Xiaonan Hong

  KEYWORDS: Angiosarcoma; Lung Metastases; Gemcitabine; Chemotherapy

  JOURNAL NAME: Journal of Cancer Therapy, Vol.4 No.4, May 31, 2013

  ABSTRACT: Introduction: For patients with anthracycline-resistant metastatic angiosarcoma, currently there is no available standard for second-line therapy and there is a need for novel effective regimens to improve response rates. Case report: We reported here about a case of a primary angiosarcoma of both breasts in a 34-year-old woman presenting lung metastases. At the completion of 3 cycles of the MAID regimen including mesna, adriamycin, ifosfamide and dacarbazine, CT showed progression of the disease (PD). Subsequently second-line chemotherapy was started using GVP regimen consisting of gemcitabine, vincristine and cisplatin. Complete response (CR) of the lung metastases was achieved after 6 treatment cycles. Conclusion: In the absence of an effective therapy among patients with anthracycline-resistant metastatic breast angiosarcoma, a GVP chemo-regimen can be performed as a selective option.