Z. X. Liu, Z. S. Song, J. L. Zhao and J. Y. Zheng, “SolidPhase Synthesis of 2-Arylamino-5-(4-Hydroxyphenyl)-1, 3,4-Thiadiazole Derivatives Based on Resin-Bound Acylhydrazines,” Phosphorus, Sulfur and Silicon and the Related Elements, Vol. 185, No. 11, 2010, pp. 2375-2381. doi:10.1080/10426501003664176

has been cited by the following article:

• TITLE: Solid Phase Synthesis of 3,4,5-Trisubstituted-1,2,4-Triazoles Derivatives from the Resin-Bound Acylhydrazines

  AUTHORS: Rongjian Xie, Xingang Liu, Chao Mai, Zhanxiang Liu

  KEYWORDS: Resin-Bound Acylhydrazine; Solid-Phase Synthesis; 1, 2, 4-Triazoles

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.3 No.1A, April 30, 2013

  ABSTRACT: An extension of our methodology on solid-phase synthesis of 3,4,5-trisubstituted-1,2,4-triazoles under mild conditions has been developed. Firstly, the resin-bound acylhydrazine is reacted with orthoesters to provide resin-bound 1,3,4-oxadiazoles. Secondly, condensation of 1,3,4-oxadiazoles resin with the corresponding arylamines hydrochloride to form the the resin-bound triazoles. 3,4,5-Trisubstituted-1,2,4-triazoles derivatives were obtained from resin-bound acylhydrazines in several steps providing 78% - 87% overall yields and excellent purity. The advantages of this method include straightforward operation and high yield and purity of the products.