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Holmes Jr., D.R., et al. (2010) ACCF/AHA clopidogrel clinical alert: Approaches to the FDA “boxed warning”: A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the American Heart Association. Circulation, 122, 537- 557. doi:10.1161/CIR.0b013e3181ee08ed

has been cited by the following article:

  • TITLE: Clopidogrel in ischemic heart disease: A critical appraisal

    AUTHORS: Mohammed A. Al-Otaiby, Abdulrahman M. Al-Moghairi

    KEYWORDS: Clopidogrel; Ischemic Heart Disease; Thienopyridine; Platelets Inhibition

    JOURNAL NAME: Health, Vol.5 No.3, March 29, 2013

    ABSTRACT: Aspirin and clopidogrel are the commonest dual antiplatelet agents being used in the secondary prevention of cardiovascular disease. In high risk patients with coronary heart disease, the use of aspirin was associated with a significant risk reduction of myocardial infarction, stroke and vascular death. The use of clopidogrel alone was slightly superior to aspirin, and associated with reduced risk of vascular death, ischemic stroke and myocardial infarction. Dual antiplatelet therapy has been well studied in patients with acute coronary syndrome and those undergoing percutaneous coronary intervention (PCI). In patients with stable coronary heart disease or multiple risk factors the combination of clopidogrel plus aspirin was not significantly more effective than aspirin alone in reducing MI, stroke or death from cardiovascular causes.