TITLE:
The prognostic impact of P wave dispersion in prediction of clinical outcome after percutaneous balloon mitarl valvuloplasty in patients with mitral stenosis and sinus rhythm
AUTHORS:
Ragab A. Mahfouz, Ashraf E. Dewedar
KEYWORDS:
P-Wave Maximum P-Wave Minimum; P-Wave Dispersion; Rheumatic Mitral Stenosis; Cardiac Events; Follow-Up
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.3 No.1,
January
24,
2013
ABSTRACT:
Objective: The aim of the study was to investigate the impact of
P-maximum and P-wave dispersion on the long term clinical outcome after
successful percutaneous balloon mitral valvuloplasty (PBMV) in patients
with mitral stenosis (MS) and sinus rhythm. Also to test the correlation between
P-variables and right ventricular function and pulmonary artery pressure before
and after PMBV. Methods: Eighty-five patients undergoing PMBV were enrolled
in this study. We evaluated P-maximum, P-minimum and P-wave dispersion before
and one month after PBMV. We studied the changes in pulmonary arterial pressure
(PAP), left atrial (LA) dimension, mitral diastolic gradient, and mitral valve
area, in addition to the changes in right ventricular function utilizing tissue
Doppler assessment both before and after PMBV, in addition the role of the
P-wave dispersion in predicttion of late cardiac events. Results: There were
significant decreases in mean diastolic gradient, PAP, and LA size and
significant improvement in right ventricular tissue Doppler indices after PMBV.
Ac- company these hemodynamic changes after PMBV. P-maximum and P-wave
dispersion were found to be decreased (P off values of ≥62.8 msec for P-wave dispersion and
118 mes for P-maximum.ROC curve showed AUC of 0.919 for P-wave dispersion
and 0.913 for P-maximum (P