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has been cited by the following article:

• TITLE: Neocollagenesis in Non-Invasive Aesthetic Treatments

  AUTHORS: Ilja L. Kruglikov

  KEYWORDS: Neocollagenesis; Aesthetic Treatments; Procollagen; Mature Collagen; Turnover

  JOURNAL NAME: Journal of Cosmetics, Dermatological Sciences and Applications, Vol.3 No.1A, January 9, 2013

  ABSTRACT: Dermal neocollagenesis is often assumed to be the main reason of visible skin improvement after different non-invasive and minimal invasive aesthetic treatments. However, the very slow dynamics of the mature collagen remodelling in the extra cellular matrix (ECM) of dermis, with a half-life time of 15 years, renders every observable upregulation of collagen production insufficient to replace a significant part of the matrix during the short time in which it is claimed skin improvement takes place.