TITLE:
Synthesis and Biological Evaluation of Novel 6-(3-(4,5-Dihydro-1,5-diphenyl-1H-pyrazol-3-yl)phenylamino) Pyridazin-3(2H)-one Derivatives
AUTHORS:
Shrikrishna D. Tupare, Satish A. Dake, Santosh V. Nalage, Sidhanath V. Bhosale, Rajita D. Ingle, Rajendra P. Pawar
KEYWORDS:
Antibacterial Activity; Antifungal Activity; Efficient Synthesis
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.2 No.4,
December
27,
2012
ABSTRACT: Pyrazoles are important nitrogen containing 5-membered heterocyclic compounds. Numerous pyrazoline derivatives have been found to possess considerable biological activities, which stimulated the research activity in this field. Several 1,3,5-Triphenyl-1H-pyrazole containing 6-aminopyridazin-3(2H)-one derivatives has been synthesized. These new compounds were characterized using IR, 1H-NMR and Mass spectra and Elemental analysis. They possess some potent biological activities. Therefore biological screening of novel compounds has been also done.