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A. Sudhindra, “Huntington’s Chorea: Implications for Nursing in India,” Nursing Journal of India, Vol. 80, No. 4, 1989, pp. 97-99.

has been cited by the following article:

  • TITLE: Measuring the Cognitive Impact of Laughter on Elderly People with Mild Cognitive Impairment in Japan

    AUTHORS: Miwa Yamamoto, Shizue Mizuno, Masako Aota, Yoko Murakami

    KEYWORDS: Cognitive Impact; Laugh; Elderly People; Mild Cognitive Impairment

    JOURNAL NAME: International Journal of Clinical Medicine, Vol.3 No.6, November 15, 2012

    ABSTRACT: Objective: To evaluate the effect of laughter on cognition in elderly with mild cognitive impairment (MCI) through an appropriately designed intervention. Methods: The intervention involved watching a Japanese comedy routine (Manzai) for approximately twenty minutes, once a week for ten weeks. Participants were asked to paint, as a simple exercise, in addition to watching the show. Twenty-seven patients with MCI from the convalescent ward of a general hospital in the Kansai region of Japan. We measured cognition by evaluating five cognitive function domains before (baseline) and after the intervention. We used the Wilcoxon signed rank test, a distribution-free method, to compare baseline and post-intervention data. Ethical Consideration: Participants were given a document explaining the study. Only those who officially agreed to participate were enrolled. Results: Mean age of patients was 85.0 ± 2.8 years; average education was 8.6 ± 2.8 years. Three cognitive function domains had significantly different average scores after the intervention: 1) Exercise: 44.4 ± 8.9 points at baseline, 36.3 ± 10.2 post-intervention (p = 0.014); 2) Word memory: 40.6 ± 7.2 at baseline, 43.1 ± 8.8 post-intervention (p = 0.002); and 3) Animal name recollection: 35.3 ± 8.4 at baseline, 38.1 ± 9.0 post-intervention (p = 0.003). Discussion: The intervention led to significantly higher cognitive scores in exercise, word memory, and animal name recollection domains, suggesting that interventions focused on laughter and simple exercise may improve cognition in elderly patients with MCI.