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Fleisher, L.A., Beckman, J.A., Brown, K.A., Calkins, H., Chaikof, E.L., Fleischmann, K.E., Freeman, W.K., Froehlich, J.B., Kasper, E.K., Kersten, J.R., Riegel, B., Robb, J.F., Smith, S.C.Jr., Jacobs, A.K., Adams, C.D., Anderson, J.L., Antman, E.M., Buller, C.E., Creager, M.A., Ettinger, S.M., Faxon, D.P., Fuster, V., Halperin, J.L., Hiratzka, L.F., Hunt, S.A., Lytle, B.W., Nishimura, R., Ornato, J.P., Page, R.L., Riegel, B., Tarkington, L.G. and Yancy, C.W. (2007) ACC/AHA 2007 guidelines on perioperative ca
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TITLE:
Prognostic implications of type 2 myocardial infarctions
AUTHORS:
Hazim El-Haddad, Elijah Robinson, Katrina Swett, Gretchen L. Wells
KEYWORDS:
Type 2 Myocardial Infarction; Postoperative Myocardial Infarction; Troponin; Sepsis
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.2 No.4,
October
30,
2012
ABSTRACT: Purpose: A type 2 myocardial infarction (MI) is due to ischemia from increased oxygen demand or decreased supply. It is not an infrequent complication following non-cardiac surgery or in the setting of acute medical illness. The purpose of this study was to determine whether type 2 MIs had a worse prognosis than a type 1 MI. Methods: The hospital database of a large terti-ary-level academic medical center was queried for all patients with a troponin I ≥ 1.6 ng/mL during a one-year period. The outcomes of patients with a type 2 MI were compared to those with a type 1 MI. Results: This retrospective study found that a type 2 MI is more lethal than the usual type 1 MI, particularly among women and the elderly. There was no statistical difference in outcomes between those that occurred in the post-operative setting compared to those that occurred in the setting of acute medical illness. Conclusions: Type 2 MIs are common and are associated with increased mortality, as compared with type 1 MIs. To date, no guidelines exist for the management of this type of MI. Further research into underlying mechanisms resulting in type 2 MI as well as potential treatment strategies is needed.
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