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Anderson, J.L., Adams, C.D., Antman, E.M., Bridges, C.R., Califf, R.M., Casey, D.E., Chavey, W.E.2., Fesmire, F.M., Hochman, J.S., Levin, T.N., Lincoff, A.M., Peterson, E.D., Theroux, P., Wenger, N.K., Wright, R.S., Smith, S.C.Jr., Jacobs, A.K., Adams, C.D., Anderson, J.L., Antman, E.M., Halperin, J.L., Hunt, S.A., Krumholz, H.M., Kushner, F.G., Lytle, B.W., Nishimura, R., Ornato, J.P., Page, R.L., Riegel, B. (2007) ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation
has been cited by the following article:
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TITLE:
Prognostic implications of type 2 myocardial infarctions
AUTHORS:
Hazim El-Haddad, Elijah Robinson, Katrina Swett, Gretchen L. Wells
KEYWORDS:
Type 2 Myocardial Infarction; Postoperative Myocardial Infarction; Troponin; Sepsis
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.2 No.4,
October
30,
2012
ABSTRACT: Purpose: A type 2 myocardial infarction (MI) is due to ischemia from increased oxygen demand or decreased supply. It is not an infrequent complication following non-cardiac surgery or in the setting of acute medical illness. The purpose of this study was to determine whether type 2 MIs had a worse prognosis than a type 1 MI. Methods: The hospital database of a large terti-ary-level academic medical center was queried for all patients with a troponin I ≥ 1.6 ng/mL during a one-year period. The outcomes of patients with a type 2 MI were compared to those with a type 1 MI. Results: This retrospective study found that a type 2 MI is more lethal than the usual type 1 MI, particularly among women and the elderly. There was no statistical difference in outcomes between those that occurred in the post-operative setting compared to those that occurred in the setting of acute medical illness. Conclusions: Type 2 MIs are common and are associated with increased mortality, as compared with type 1 MIs. To date, no guidelines exist for the management of this type of MI. Further research into underlying mechanisms resulting in type 2 MI as well as potential treatment strategies is needed.
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