TITLE:
Sciatic Nerve Block with Ropivacaine and Prilocaine in a Patient with Chronic Progressive External Ophthalmoplegia (CPEO)
AUTHORS:
Heiko Baumann, Eduard Schlegel, Fabian Wagner, Jürgen Biscoping
KEYWORDS:
Local Anesthetics; Mitochondrial Myopathy; Sciatic Nerve Block; Pharmacology; Anesthetic Management
JOURNAL NAME:
Open Journal of Anesthesiology,
Vol.2 No.4,
September
5,
2012
ABSTRACT: The anesthetic implications of caring for patients with mitochondrial myopathies (MM) are not well defined, and the few case reports that have been published are contradictory. Local anesthetics particularly have the potential to worsen neuromuscular manifestations via direct effects on mitochondrial bioenergetics. Here we describe the anesthetic management of a patient with chronic progressive external ophthalmoplegia (CPEO) in which a sciatic nerve block with ropivacaine and prilocaine was performed and review the available related literature.