D. A. Thorne, F. L. Datz, K. Remley, et al., “Bleeding Rates Necessary for Detecting Acute Gastrointestinal Bleeding with Technetium-99m-Labeled Red Blood Cells in an Experimental Model,” Journal of Nuclear Medicine, Vol. 28, No. 4, 1987, pp. 514-520.

has been cited by the following article:

• TITLE: Rethinking an Algorithm: The Utility of the Techinicium 99 m Labeled Red Cell (RBC) Scanning for Lower Gastrointestinal Bleeding (LGIB)

  AUTHORS: Shaffer R. S. Mok, Chijioke Ojiako, Ankur Kalra, Mithil Gajera, Sri Sujanthy Rajaram

  KEYWORDS: Technicium 99 m; Lower Gastrointestinal Bleed; LGIB; Tc-99 m

  JOURNAL NAME: International Journal of Clinical Medicine, Vol.3 No.2, March 16, 2012

  ABSTRACT: Purpose: Technetium 99 m (99 m Tc) labeled scan is often done to localize bleeding to facilitate treatment. No level 1 or 2 data supports this approach. The aim of this study was to determine the correlation between site of bleeding by nuclear scan and findings at surgery, angiogram or colonoscopy. Methods: Records of patients admitted to Cooper University Hospital from January 2001-December 2005 with LGIB who had 99mTc scan were analyzed. Results: 164 of 170 patients were eligible to be evaluated. There were 45 positive (27.5%) and 119 negative scans (72.5%). 21 of 45 patients with positive scans had angiography. 7 patients (33.3%) had positive and 14 (66.6%) negative angiograms. In 6 patients (85.7%) with (+) angiograms, there was correlation on the area of bleed as seen on the 99 m Tc scan (p = 0.125). 20 patients, in the positive scan group, required surgery. In 15 (75%) the findings at surgery correlated with the scan result (p = 0.04). 31 patients (68.8%) with positive scan had colonoscopy. There was correlation in 27 patients (87.0%) (p