R. Hague, “What is the Threat from Extended Spectrum Beta-Lactamase-Producing Organisms in Children?” Archives of Disease in Childhood, Vol. 96, 2011, pp. 325-327. doi:10.1136/adc.2010.184911

has been cited by the following article:

• TITLE: Appendical Perforation by Infection with Extended-Spectrum Beta-Lactamase (ESBL)-Producing Escherichia coli: Case Report

  AUTHORS: Hisayuki Miyagi, Tadao Okada, Shohei Honda, Masashi Minato, Akinobu Taketomi

  KEYWORDS: Appendicitis; ESBL (Extended-Spectrum Beta-Lactamase)-Producing E. coli; Abscess; Meropenem

  JOURNAL NAME: Surgical Science, Vol.3 No.1, January 13, 2012

  ABSTRACT: We report the very rare case of a huge appendical abscess with extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli (E. coli) as the pathogen. There have been several reports of appendical infections such as appendicitis and appendical abscess caused by ESBL-producing bacteria in adults. The treatment of ESBL-producing E. coli infection is specific, and ESBL-producing bacteria have recently been reported as pathogens associated appendicitis in children. To the best of our knowledge, this is the second report of perforated appendicitis with abscess due to ESBL-producing E. coli. We discuss the diagnostic modalities and treatments for appendical abscess with ESBL-producing E. coli. and propose that the patients with perforated appendicitis and abscess formation due to ESBL-producing E. coli should be administered the antibiotic MEPM within 2 weeks to treat the abscess more effec-tively without producing other multidrug-resistant bacteria.