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has been cited by the following article:

• TITLE: Trans-Frame Aortic Regurgitation of New-Generation Aortic Bioprosthesis

  AUTHORS: Michael Timothy Simpson, Kasmir Ramo, Vinayak Bapat, Andrea Miltiades, Isaac George

  KEYWORDS: Aortic Valve Replacement, Bicuspid Aortic Valve, Paravalvular Leak

  JOURNAL NAME: World Journal of Cardiovascular Surgery, Vol.14 No.4, April 30, 2024

  ABSTRACT: A widely used aortic valve bioprosthesis is susceptible to regurgitation between the sewing ring and the frame of the valve due to its relatively thin fabric coverage. In some cases this leak has been shown to resolve with administration of protamine, however, tension on this area from annular sutures placed in an asymmetric bicuspid valve annulus may exacerbate the defect.