TITLE:
Chronic Hepatitis B Virus Infection: Biological Parameters in Patients Treated with Tenofovir Disoproxil Fumarate
AUTHORS:
Sanra Déborah Sanogo, Moussa Y. Dicko, Lamine N’Diaye, Ousmane Diarra, Drissa Katilé, Abdoulaye Maiga, Ouatou Mallé, Sabine Drabo, Makan S. Tounkara, Hourouma Sow, Kadiatou Doumbia, Anselme Konaté, Moussa T. Diarra
KEYWORDS:
Viral Hepatitis B, Tenofovir, Biological Parameters
JOURNAL NAME:
Open Journal of Gastroenterology,
Vol.14 No.4,
April
29,
2024
ABSTRACT: Chronic hepatitis B causes a liver disease characterized by inflammation of the liver parenchyma. The aim of this study was to investigate the evolution of biological parameters in patients treated with Tenofovir for chronic B infection at the Commune V referral health center in Bamako. We obtained a prevalence of 14.15%. The most represented age group was 31 - 40 years, with 36.8%. The sex ratio was 1.44 in favour of men. Viral load was undetectable after 18 months of treatment in 25 patients (42.37%). Tenofovir, the 1st-line drug in Mali, is effective on the biological parameters monitored in patients.