TITLE:
Evolution of Viral Load in Patients Infected with HIV-1 at Point G University Hospital
AUTHORS:
A. Maiga, D. Kone, D. M. Coulibaly, Ag M. Baraika, A. Traore, S. S. Diakite, I. I. Maiga, I. Konate, A. I. Maiga
KEYWORDS:
HIV-1, Treatment, Viral Load, Point G University Hospital
JOURNAL NAME:
Open Journal of Medical Microbiology,
Vol.14 No.1,
March
29,
2024
ABSTRACT: Introduction: HIV, the human
immunodeficiency virus, is the etiological agent of acquired immunodeficiency
syndrome (AIDS). The aim of this study was to assess the evolution of the viral
load in patients under treatment. Methodology: This was a study carried
out from July 2017 to June 2022 at the Point G University Hospital laboratory.
The determination of the viral load of patients was carried out by PCR on the
ABOTT M2000sp/rt platform. Results: A total of 129 patients infected
with HIV-1, aged 19 to 72 years with a mean age of 40.05 years ± 10.71; all on
antiretroviral chemotherapy. The female gender predominated among our patients.
The most common treatment regimen was 2INTI + 1INNTI with 72.9% followed by
2INTI + 1INI with 13.2%. As for the combinations of molecules, the combination
TDF + 3TC + EFV and TDF + 3TC + DTG predominated, respectively 65.1% and 13.2%.
89.9% of our patients had undetectable viremia after 12 months of treatment (p 1616908.484 to M0 at 5742.36 copies /ml ± 35756.883 at M12 (p Conclusion: Generally speaking,
antiretroviral treatment had contributed to controlling viral loads, however
the therapeutic combination TDF + 3TC + DTG had made it possible to obtain more
patients with undetectable viremia instead.