TITLE:
Pneumatosis Cystoides Intestinalis Complicated during Chemotherapy for Pulmonary Nontuberculous Mycobacterial Disease
AUTHORS:
Yoshihiro Kobashi, Toru Oga
KEYWORDS:
Pneumatosis Cystoides Intestinalis (PCI), Pulmonary Nontuberculous Mycobacterial (NTM) Disease, Combined Chemotherapy
JOURNAL NAME:
Journal of Tuberculosis Research,
Vol.11 No.3,
September
7,
2023
ABSTRACT: Background: Pneumatosis cystoides intestinalis (PCI) is a rare disease
characterized by the presence of gas in the intestinal wall. Aim: We
report two rare cases of PCI that are complicated during the chemotherapy for
pulmonary nontuberculous mycobacterial (NTM) disease. Case Presentation:
In this report, we described two cases (a 72-year-old woman and a 60-year-old woman) of PCI that
appeared during the combined chemotherapy consisting of rifampicin, ethambutol
and clarithromycin. Because there were few clinical symptoms and increased
inflammatory responses, the diagnosis of PCI was delayed. However, there were
fortunately no severe complications in both cases. Conclusion:
Respiratory physicians should be aware of the potential development of PCI in patients during the chemotherapy for pulmonary NTM disease. It is important to detect PCI in the early stage through
radiological examinations to avoid severe complications.