TITLE:
Severe Hypophosphatemia in Adolescent Cannabis User
AUTHORS:
Chantel Johnson, Michael J. Thomas, Michael Halata, Dmitry Samsonov
KEYWORDS:
Cannabinoid, Toxicity, Hyperemesis
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.13 No.4,
July
17,
2023
ABSTRACT: Cannabinoid hyperemesis syndrome (CHS) involves cyclical nausea,
vomiting, and abdominal pain linked to use of cannabis with resolution of
symptoms upon cessation of cannabinoids. Although electrolyte disturbances,
fluid imbalances, and nutritional deficiencies are known complications of CHS
in the setting of intractable vomiting, severe hypophosphatemia is a rare
clinical phenomenon cited primarily in the adult literature. Pediatric cases
are scarcer, thus the magnitude associated with our patient case describes an
adolescent diagnosed with CHS complicated by recurrent severe hypophosphatemia.
As cannabis accessibility and potential for abuse increase with the wave of
legalization seen at the state level, clinician awareness is needed for such
adverse entities related to cannabinoid toxicity.