TITLE:
Blood Glucose Reference Interval in Mus musculus Mice
AUTHORS:
Joseph Kangudia Mbaya, Damien Mbanzulu Pita Nsonizau, Nene Mbanzulu Nsolani, Thierry Zosuruna Mbuy
KEYWORDS:
Fasting Blood Glucose, Reference Intervals, Mus musculus, Embryotoxicity
JOURNAL NAME:
Open Access Library Journal,
Vol.10 No.6,
June
30,
2023
ABSTRACT: The analysis of the carbohydrate status of Mus musculus mice is necessary for an experimental study of embryotoxicity in an animal model because to date several studies have revealed a frequent association between disorders of glycoregulation and various congenital malformations. The objective of this study is to determine the reference intervals of glycaemia in young Mus musculus mice intended for the study of embryotoxicity. This is an experimental study carried out at the Human Embryology Laboratory of the University of Kinshasa in May 2021 on 20 mice, Mus musculus adults (10 males and 10 females), in good health, weighing 20 and 30 grams in which a dosage fasting blood glucose test was performed. The effect of gender on blood glucose was assessed and reference intervals (RI) were established using a parametric method with p Mus musculus animal model for embryotoxicity studies with impaired glycoregulation.