TITLE:
Epidemic to Different Strains of SERRATIA: Experience of Neonatal Intensive Care Unit: About 30 Cases
AUTHORS:
Fatima-Ezzahra Tahiri, Abdessamad Lalaoui, Hasna Rafi, Fatiha Bennaoui, Nadia El Idrissi Slitine, Nabila Soraa, Fadl Marabih Rabou Maoulainine
KEYWORDS:
Epidemic, Neonatal Resuscitation, Nosocomial Infection, Serratiamarcesens, Serratiaureitylica, Serratia Nematodiphila, Antibiotic Resistance
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.13 No.2,
March
23,
2023
ABSTRACT: Serratia
is an opportunistic pathogenic bacterium of the Enterobacteriaceae family,
occasionally responsible for epidemics of nosocomial infections in critical
departments; in
particular in neonatal intensive care units Enterobacteriaceae form a large
family of Gram-negative bacteria, which cause diseases of highly variable
severity, due to distinct pathogenic mechanisms. This family is heterogeneous
as it consists of about 30 genera of bacteria and more than 100 species.
However, all these germs have in common their preferential location in the
digestive system, some being part of the normal flora although they are also
present in the environment. Several metabolic processes characterize this
bacterial family. These include the ability to reduce nitrate to nitrite (for
energy generation), ferment glucose, lack cytochrome oxidase, be aerobic or
anaerobic, motile or immobile, … Enterobacteriaceae constitute more than 80% of the germs isolated in the
laboratory: Escherichia, Salmonella, Shigella, Klebsiella, Enterobacter, Serratia, Proteus, Morganella and Yersinia are the rods most often found. Regarding nosocomial
infection to Serratia, this bacterium colonizes the respiratory, digestive and
urinary systems of patients, mainly responsible for bacteremia, infections of
the lower respiratory tract, urinary and skin infections. Through our work, we report the epidemic
experienced in the neonatal intensive care unit MOHAMMED VI university
hospital, mother-child hospital MARRAKECH MOROCCO for three months from
December at February 2023 interesting 30 newborns whose clinical presentation
was different, the positive diagnosis was based on blood and geographical
samples taken by the bacteriology department to isolate the offending germs,
the therapeutic management of our patients consisted essentially of various
hygiene measures in association with dual antibiotic therapy based on meropenem
and amikacin. The evolution was marked by the death of 21 patients (70%) and the recovery of 9 patients (30%). The prognosis of infection by serratia remains
bleak with high morbidity interest in prevention by respecting the rules of
hygiene, which begins with hand disinfection.