TITLE:
Risk Factors Associated with Cholelithiasis during Pregnancy and Postpartum
AUTHORS:
Shaimaa Belal, Hesham Mohammed Hamed, Abdelrahman Kamal, Manal Abdel-Wanees Al-Sayed, Hany Mahmoud Abd El Hamid
KEYWORDS:
Cholelithiasis, Pregnancy, Postpartum
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.12 No.11,
November
15,
2022
ABSTRACT: Gallbladder disease is the most common non-obstetrical cause of maternal hospitalization in the first year postpartum. Many risk factors have
been associated with gallbladder disease in pregnancy including body mass
index, prenatal weight gain, prenatal physical activity, dietary fat, age,
parity, a history of gallbladder disease and the number of previous pregnancies
were significant factors related to new
gallstones and biliary sludge formation in the pregnant group. The aim
of this study is to evaluate the risk factors for gallstones formation in
pregnancy and one year after labour. The study included 328 female patients (pregnant or postpartum) divided into two groups;
patient group (164 patient) that are pregnant or postpartum
patient have gallstones and control group (164 patient) that are pregnant
or postpartum patient does not have gallstones. All patients were subjected to full history taking; especially about risk factors
predisposing for gallstones, physical examination and pre-operative routine laboratory
investigations and imaging as abdominal ultrasound study (U/S). Obesity, young
age, history of gallbladder disease and use
of estrogen and progesterone are the main risk factors that increase incidence of gallstones during pregnancy or
one year postpartum. Use of vit C, iron, drinking coffee and practicing regular
physical activity are considered protective factors.