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has been cited by the following article:

• TITLE: Evaluation of Analgesic and Antipyretic Effects of the Aqueous Extract of the Leaves of Chenopodium ambrosioides L. (Amaranthaceae)

  AUTHORS: Elion Itou Romaric De Garde, Etou Ossibi Arnaud Wilfrid, Tchiama Loui-Marie, Boukongo Roger Pavel, Mambeke Hono Roger, Morabandza Cyr Jonas, Abena Ange Antoine

  KEYWORDS: Analgesic, Antipyretic, Medicinal Plant, Chenopodium ambrosioides

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.10 No.11, November 15, 2022

  ABSTRACT: C. ambrosioides is a Congolese medicinal plant used in the treatment of several pathologies. This work was initiated to evaluate the analgesic and antipyretic effect of the aqueous extract of leaves of C. ambrosioides. Analgesic effect was evaluated by using the acetic acid-induced writhing, the Tilk Flick test as well as the pain induced by formaldehyde. The results obtained showed that the aqueous extract significantly reduces the number of abdominal writhes (p C. ambrosioides (400 and 600 mg/kg) compared to control group (saline water). This result suggests an antipyretic effect. Chemical screening revealed the presence of alkaloids, flavones and mucilage. The presence of alkaloids and flavones could explain the analgesic and antipyretic effects attributed to this aqueous extract.