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has been cited by the following article:

• TITLE: Synthesis, Biological Evaluation, and SAR Studies of Varyingly Substituted 4-Thioflavonols

  AUTHORS: Rubina Bibi, Amina Sadiq, Ehsan Ullah Mughal

  KEYWORDS: Flavonols, 4-Thioflavonols, Flavonoids, Lawsons Reagent, Antibacterial Activity, Antifungal Activity, One Pot Synthesis, Sulfur Compounds, SAR Studies

  JOURNAL NAME: Open Journal of Medicinal Chemistry, Vol.12 No.2, June 30, 2022

  ABSTRACT: A series of 4-thioflavonols compounds were synthesized by treating flavonols with lawsons reagent with variable substituent groups at A, B, and AB rings. All the synthesized compounds were checked for antibacterial and antifungal activity. We report that many compounds were found active against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus, bacterial strains and, C. albicans, C. parapsilosisstrains and C. krusei fungal strains. Most of the synthesized 4-thioflavonols compounds were found to show enhanced antimicrobial activity than respective flavonol compounds.