Tokarev, A.A., Butylin, A.A. and Ataullakhanov, F.I. (2011) Platelet Adhesion from Shear Blood Flow Is Controlled by Near-Wall Rebounding Collisions with Erythrocytes. Biophysical Journal, 100, 799-808.
https://doi.org/10.1016/j.bpj.2010.12.3740

has been cited by the following article:

• TITLE: Evaluation of Red Blood Cell Contribution to Platelet Activation in the Bulk Applying Red Blood Cell—Platelet Thrombus as a Point Source Model

  AUTHORS: Taha M. Alkhamis, Bahieh M. Alma’atah

  KEYWORDS: Platelet, Red Blood Cell, Aggregation, Adhesion, Diffusion, ADP, Point Source, Chemical Contribution, Physical Contribution, Shear Stresses, Hemolysis

  JOURNAL NAME: Advances in Bioscience and Biotechnology, Vol.13 No.2, February 24, 2022

  ABSTRACT: In this study, a point source mathematical model is proposed to describe the diffusion of adenosine di-phosphate (ADP) from either damaged red blood cell (RBC) or activated platelet. The convective diffusion equation is reduced to describe the suggested problem. The final differential equation is solved using Laplace transforms and ADP concentration profiles around the source are obtained. Thrombi of 5 to 20 μm3 containing platelets and a range of red blood cells (RBCs) (0%, 25%, 50%, 75%, 100%) concentrations are used to apply the model. Reported ADP concentrations in the literature are used and its dynamic release from the point source is calculated. Results suggest that RBC chemical contribution to platelet aggregation in the bulk is much less than that of platelet (almost) negligible. However, the physical effect of RBCs is dominant in the bulk through augmentation of released ADP and platelets diffusivities. Moreover, the chemical contribution reported in previous studies is suggested to be as a result of interaction of RBC with the surface under the influence of shear stresses in the boundary region.