TITLE:
Study on Circulating Tumor Cells and Various Clinical Features and Blood-Related Indexes in Patients with Renal Cancer
AUTHORS:
Dianbin Song, Zhiyong Wang, Xiuming Li, Jingjing Zhan, Qiang Chi, Hui Xu, Hongyang Li, Ying Liu
KEYWORDS:
Kidney Cancer, Circulating Tumor Cells, Clinical Features, Test Indicators
JOURNAL NAME:
Surgical Science,
Vol.13 No.1,
January
25,
2022
ABSTRACT: Objective: To investigate the value of CTC clinical features and blood-related test
indicators in renal cancer patients by detecting the number of circulating
tumor cells (CTC) in patients with renal cancer. Methods: To analyze 59 patients with renal cell carcinoma (RCC) admitted to the
Department of Urology, Affiliated Hospital of Chengde Medical College from May
2018 to October 2019. According to the CTC count (5 pcs/3.5 ml),
they were divided into CTC positive group and CTC negative group. The age,
gender, tumor location, tumor size, hematuria, CEC (circulating endothelial
cells), CTC Cluster (aggregate), gene mutation, platelet (PLT), albumin (ALB),
hemoglobin (HB), alkaline phosphatase (AKP), lactate dehydrogenase (LDH) were
compared between the two groups of patients and the correlation of the number
of CTCs. Results: There were significant differences in tumor size,
CEC, and gene mutations between the two groups (P Conclusion: The number of CTC in RCC patients is correlated with some clinical
features (tumor size, CEC, gene mutation) and some related test indicators (HB,
PLT, LDH), and can be combined with the above related indicators to predict the
occurrence, metastasis and prognosis of renal cancer.