de Buy Wenniger, L., Scheltema, J., Verheij, J. and Beuers, U. (2013) Testicular Inflammation as a New Manifestation of IgG4-Associated Disease. Urology, 82, e15-e16.
https://doi.org/10.1016/j.urology.2013.04.046

has been cited by the following article:

• TITLE: Isolated Autoimmune Orchitis Due to IgG4 Hypersecretion Presenting as Tumor-Like Mass: Case Report and Review of Literature

  AUTHORS: Francisco Marcos da Silva Barroso, Flavio Antunes de Sousa, Paloma Menezes de Souza, Gustavo Lopes de Castro, Katia Ramos Moreira Leite, Monique Freire Santana, Roger Arthur da Cunha Alves, Gabriela Ayumi Owada Borges, Juan Eduardo Rios Rodriguez

  KEYWORDS: Orchitis, IgG4-Related Disease, Autoimmune, Testicle, Inflammatory

  JOURNAL NAME: Open Journal of Urology, Vol.12 No.1, January 17, 2022

  ABSTRACT: Background: IgG4-related disease is a rare autoimmune condition that presents with lymphoplasmacytic infiltrate and fibrosis in the organ affected. Isolated testicle involvement is uncommon and there are only a few cases reported in the literature. Case Presentation: We report a case of isolated chronic orchitis due to IgG4 hypersecretion in a 61-year-old patient that evolved with asymptomatic tumor-like mass growth and was treated with left orchiectomy. Histopathological study revealed orchitis related to IgG4 hypersecretion disease. Conclusion: IgG4-related disease can be manifested as a multi or single-organ disorder. Most diagnoses are made after surgery with histopathological analysis. Most of the cases in literature stand out the difficulty in diagnosis and necessity of high suspicion due to this condition’s similarity with neoplasm presentation.