TITLE:
Brainstem Tuberculoma Reactivated during Pregnancy and Postpartum
AUTHORS:
D. Kanikomo, M. Diallo, A. Tokpa, I. Sango, Y. Sogoba, M. S. Diarra, B. Sogoba, M. Dama, O. Coulibaly, M. Coulibaly, M. Diallo
KEYWORDS:
Tuberculosis, Central Nervous System, Reactivation, Pregnancy
JOURNAL NAME:
Open Journal of Modern Neurosurgery,
Vol.12 No.1,
December
9,
2021
ABSTRACT: Pregnancy, which is responsible for the decline in immunity, and the immediate postpartum period can lead to reactivation or worsening of tuberculosis. We report a case of a patient who consulted for neurological disorders in the context of a deterioration in general condition. The CT scan revealed a brainstem lesion which was successfully treated like a tuberculosis. However, reactivation has been observed in the postpartum period of a pregnancy contracted during anti-tuberculosis treatment. Further clinical improvement has been achieved with anti-tuberculosis treatment. Pregnancy and the immediate postpartum had led to a transient decline in immunity in part by decreasing in the inflammatory activity of type 1 helper T cells so that the fetus, which is a foreign body, was accepted by the maternal body. This decline in immunity during pregnancy and the immediate postpartum period due to immune reconstitution had been responsible for a high degree of vulnerability, usually characterized by a significant exacerbation of tuberculosis symptoms and an unfavorable course of disease.