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has been cited by the following article:

• TITLE: TCCA/NCS-Promoted Cascade Cyclization of β, γ-Unsaturated Compounds: Synthesis of Isoxazolines and Pyrazolines

  AUTHORS: Khidir Tajelseir Othman, Nibras Ahmed Elaas

  KEYWORDS: 2-Isoxazolines, 2-Pyrazolines, NCS, TCCA

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.11 No.4, November 18, 2021

  ABSTRACT: 2-Isoxazolines and 2-pyrazolines have been derived from oxime and hydrazone derivatives reacted with N-chlorosuccinimide (NCS) and trichloroisocyanuric acid (TCCA). Cyclization strategy is developed for the reaction of β, γ-unsaturated hydrazones with the TCCA to drive 2-pyrazolines and the reaction of β, γ-unsaturated oximes with NCS to derive 2-isoxalzolines. Structures of all new 2-isoxazolines and 2-pyrazolines have been elucidated by microanalyses, 1H, 13C NMR and Mass spectroscopies.