Kan, Y., Anno, T., Kawasaki, F., Takai, M., Shigemoto, R., Kaneto, H., Kaku, K. and Okimoto, N. (2017) Bilateral Lower Limb Edema Induced by Rapid Improvement of Glycemic Control with Insulin Therapy in a Subject with Poorly Controlled Type 2 Diabetes. Acta Diabetologica, 54, 611-613.
https://doi.org/10.1007/s00592-017-0997-7

has been cited by the following article:

• TITLE: Type 1 Diabetes Mellitus Patient Presented with Insulin Edema only after Intensive Lifestyle Changes: A Case Report and Brief Review of the Literature

  AUTHORS: Aida Al Jabri, Zahra Buali

  KEYWORDS: Insulin Edema, Type 1 Diabetes, Type 2 Diabetes

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.10 No.11, November 11, 2021

  ABSTRACT: Insulin edema is considered a rare type of generalized edema that occurs after initiation or intensification of insulin treatment in patients with diabetes mellitus (DM). In this case report, we present a clinically significant edema that developed following a dramatic improvement in glycemic control after intensive improvement in lifestyle in a 13-year-old girl, with type 1 DM confirmed by positive anti-glutamic acid decarboxylase (anti-GAD) antibodies. She had poor glycemic control during 2 years of insulin therapy, and following lifestyle improvements (with no changes to her medications types or doses), she developed generalized body edema, and facial puffiness that resolved spontaneously, without any intervention.