TITLE:
Dosimetric Comparison: Volumetric Modulated Arc Therapy (VMAT) and 3D Conformal Radiotherapy (3D-CRT) in High Grade Glioma Cancer—Experience of Casablanca Cancer Center at the Cheikh Khalifa International University Hospital
AUTHORS:
Imane Benali, Othmane Kaanouch, Asmaa Naim, Hanae El Gouach, Zineb Dahbi, Fadila Kouhen
KEYWORDS:
HGG, IMRT, 3D-CRT, Dosimetric Study
JOURNAL NAME:
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology,
Vol.10 No.2,
May
31,
2021
ABSTRACT:
Background: Intensity Modulated Radiation Therapy (IMRT) is currently employed as a
major arm of treatment in multiforme glioblastoma (GBM). The present study
aimed to compare 3D-CRT with IMRT to assess tumor volume coverage and OAR
sparing for the treatment of malignant
gliomas. Materials and methods: We assessed 22 anonymized
patients datasets with High Grade Glioblastoma who had undergone post-operative Intensity
Modulated Radiotherapy (IMRT) and 3D Conformal Radiotherapy (3D-CRT), This
study will compare and contrast treatment plans Rapidarc and 3D-CRT to
determine which technology improves
significantly dosimetric parameters. Results: Plans will be assessed by
reviewing the coverage of the PTV using mean, maximum and minimum doses while
the OAR doses will be compared using the maximal doses for each, as set out in
the QUANTEC dose limits. Conclusion: The use of IMRT seems a superior
technique as compared to 3D-CRT for the treatment of malignant gliomas having
the potential to increase the dose to the PTV while sparing OARs optimally.