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https://doi.org/10.1021/ja800999u

has been cited by the following article:

• TITLE: Synthesis and Characterization of Zinc Oxide and Zinc Oxide Doped with Chlorine Nanoparticles as Novel α-Amylase Inhibitors

  AUTHORS: A. Al-Arfaj Ahlam, N. Abd El-Rahman Soheir

  KEYWORDS: Zinc Oxide Nanoparticles, Zinc Oxide Nanoparticles Doped with Chlorine, Crystallinity, Anti-Diabetic Activity, α-Amylase Inhibitors

  JOURNAL NAME: Food and Nutrition Sciences, Vol.12 No.3, March 29, 2021

  ABSTRACT: In this study we used a chemical solution method from oxalic acid (OX. acid) and zinc acetate (ZnAc) to prepare Zinc Oxide nanoparticles (ZnONPs) and Zinc Oxide nanoparticles doped with Chlorine (Cl:ZnONPs). The characterizations (FTIR, X-ray, SEM, TEM) of ZnONPs and Cl:ZnONPs were determined. Amylase inhibitors of ZnONPs and Cl:ZnONPs also were determined. SEM indicated that the ZnONPs and Cl:ZnONPs have an average particle size of 46.65 - 74.64 nm. TEM images of the ZnONPs and Cl:ZnONPs showed the round shaped. Compounds b, d and e exhibited significant inhibitory activity against amylase enzyme (from 69.21 ± 1.44 to 76.32 ± 0.78), respectively, and were comparable with that of acarbose (86.32 ± 0.63) at 1000 μg, thereby, projecting ZnONPs and Cl:ZnONPs as α-amylase inhibitors.