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https://doi.org/10.1016/j.fct.2013.04.025

has been cited by the following article:

• TITLE: Free Radical Scavenging, Enzyme Inhibitory and Anti-Staphylococcus aureus Properties of the Fruiting Bodies of Ganoderma lucidum, Lingzhi Mushroom

  AUTHORS: Md. Moyan Uddin PK, Mohammad Sayful Islam, Shariful Haque, Lutfa Akther, Rumana Pervin

  KEYWORDS: Ganoderma lucidum, Mushroom, Antioxidant Activity, Enzyme Inhibitory Activity, Anti-Staphylococcus aureus Activities

  JOURNAL NAME: Pharmacology & Pharmacy, Vol.12 No.3, March 22, 2021

  ABSTRACT: The current study evaluated the antioxidant, α-amylase inhibitory and anti-Staphylococcus aureus activities of the fruiting bodies of Ganoderma lucidum. Methanolic extract of G. lucidum (MEGL) was investigated for its in vitro antioxidant activity using 1,1-diphenyl 2-picrylhydrazyl (DPPH) assay and EC50 value was determined. α-Amylase inhibitory and anti-S. aureus activities were carried out by conventional methods. The mushroom extract showed maximum free radical scavenging activity at a dose of 500 μg/mL with EC50 value of 22.1399 μg/mL. EC50 value for the inhibition of α-amylase activity was found 22.6011 μg/mL. G. lucidum extracts exhibited a concentration-dependent Anti-S. aureus activity. The vast differences of this inhibition between lower and higher doses were assessed significantly (p G. lucidum has moderate antioxidant, α-amylase inhibitory, and anti-S. aureus activities. Thus this mushroom may be the alternative plant source for the antioxidant, anti-diabetic and antibacterial agents and further in vivo studies and isolation of bioactive compounds are required.