TITLE:
The Role of Black Rice Bran (Oryza sativa L. “Sembada Hitam”) on Levels of Malondialdehyde in Induction Human Umbilical Vein Endothelial Cell Serum Preeclampsia
AUTHORS:
David Randel Christanto, Johanes C. Mose, Tety Yuniarti, Muhammad Begawan Bestari, Yekti Asih Purwestri, Prima Nanda Fauziah
KEYWORDS:
Antioxidant, Black Rice Bran, MDA, Preeclampsia, TBARS
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.10 No.12,
December
14,
2020
ABSTRACT: Preeclampsia is a multisystem disorder that contributes
to morbidity and mortality worldwide. Recent studies show that elevated plasma and
erythrocytic malondialdehyde (MDA), a marker of lipid peroxidation, has been documented
in women with established preelampsia. This
study aimed to observe antioxidant properties of black rice bran on preeclampsia. Level of MDA was measured with TBARS (thiobarbituric
acid-reactive substances). Results showed that black rice bran has antioxidant
properties by significantly decreasing MDA in preeclampsia-induced HUVEC. This makes
black rice bran a promising agent which can be further used in preeclampsia treatment.