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https://doi.org/10.1007/s00109-004-0585-5

has been cited by the following article:

• TITLE: C-Reactive Protein Gene Polymorphisms Correlated with Serum CRP Levels of Diesel Engine Exhaust-Exposed Workers

  AUTHORS: Liping Zhang, Huawei Duan, Xiaomei Zheng, Ping Bin, Yuxin Zheng

  KEYWORDS: Diesel Engine Exhaust, C-Reactive Protein, Single-Nucleotide Polymorphisms, Long-Term Exposure

  JOURNAL NAME: Health, Vol.12 No.6, June 24, 2020

  ABSTRACT: Objective: To assess the association between circulating C-reactive protein (CRP), and CRP polymorphisms in the diesel engine exhaust (DEE)-exposed workers. Methods: In 137 DEE-exposed workers and 127 unexposed comparable control workers, six urinary mono-hydroxylated polycyclic aromatic hydrocarbons (OH-PAHs) and serum CRP levels were assayed. Genotyping of four CRP single-nucleotide polymorphisms (SNPs) was measured. Results: Serum CRP levels increased in exposed versus control workers (all p Conclusions: Our findings suggest that polymorphisms in CRP and circulating CRP involved in the inflammatory process may play significant roles in human sensitivity to lung function injury caused by DEE exposure. This study will help investigate the underlying mechanisms of adverse respiratory effects induced by DEE.