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https://doi.org/10.3923/jas.2006.2312.2316

has been cited by the following article:

• TITLE: The Correlation between the Intrinsic and Extrinsic Molecular Markers in the Inhibition of the Lungs Carcinogenesis Growth by Mahkota Dewa Polyphenols on Balb/c Mouse

  AUTHORS: Theopilus Watuguly, Kustarini Samsuria Indranila, Suharyo Hadisaputro, Edi Dharmana, Lyle E. Craker

  KEYWORDS: Polyphenols, Lungs Carcinogenesis, Molecular Markers, p53, Bcl-2, Bax, Caspase-8, Caspase-9, Caspase-3

  JOURNAL NAME: Open Journal of Applied Sciences, Vol.10 No.6, June 2, 2020

  ABSTRACT: Phytochemical analysis shows that mahkota dewa fruit contains polyphenols. Mahkota dewa polyphenols have the ability to disrupt or reverse the stages of cancer or a carcinogenesis process by affecting the intracellular signaling tissue molecules involved in an initiation and/or promotion. This chemopreventive potential is highly anticipating. The use, effectiveness, and benefits of the polyphenol have been empirically and pre-clinically proved without side effects. A multivariate analysis using Spearman’s test was conducted to examine the correlation between variables. Meanwhile, to determine which dependent variables played the strong role, a discriminant function analysis was performed with a significance level of p