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Ganesh, A., William, R.R., Mitra, S., et al. (2001) Orbital Involvement in Sickle Cell Disease: A Report of Five Cases and Review Literature. Eye, 15, 774-780.
https://doi.org/10.1038/eye.2001.248

has been cited by the following article:

  • TITLE: Acute Orbitopathy Manifesting as Periorbital Cellulitis in Sickle Cell Disease

    AUTHORS: Adeeb Khawaji, Hanin Alsini

    KEYWORDS: Sickle Cell Disease, Orbital Cellulitis, Orbital Infarction, Sickle Cell Orbitopathy

    JOURNAL NAME: Case Reports in Clinical Medicine, Vol.9 No.6, June 1, 2020

    ABSTRACT: Sickle cell disease is a hemoglobinopathy that results in paroxysmal vascular occlusion and tissue infarction that can manifest in a plurality of tissues. Vasoocclusive crises in sickle cell disease commonly involve bone marrow of the long bones and vertebrae. Involvement of bones with less marrow space, including the bones of the orbit, is reported rarely in the literature and can closely mimic orbital cellulitis, both clinically and radiologically. The present case is a 3 years old boy, a known case of sickle cell disease, who presented with what was thought to be orbital cellulitis and was treated accordingly. Subtle radiologic features of sickle cell orbitopathy were initially overlooked, resulting in an incorrect diagnosis and a treatment delay for the patient. Correctly treated most cases resolve with no adverse effects. This case highlights the importance of maintaining a high index of suspicion in patients with known sickle cell disease, even when the presentation is not classic.