TITLE:
Sexual and Urinary Disorders after Treatment of Rectal Cancer by Radiotherapy and Surgery at the Dantec University Hospital of Dakar
AUTHORS:
Mouhamadou Bachir Ba, Papa Macoumba Gaye, Karim Konate, Ahmadou Dem
KEYWORDS:
Sexual, Urinary Disorders After, Rectal Cancers
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.11 No.5,
May
19,
2020
ABSTRACT: We
performed a descriptive retrospective study of sexual and urinary disorders
after treatment of rectal cancer by radiotherapy and/or surgery at the Dantec
University Hospital in Dakar from 2008 to 2015. The objective of the study was
to evaluate these sexual and urinary complications and the factors influencing
it. We have collected 50 patients. The average age of is 55.7 years with a sex
ratio of 0.78. The dominant clinical signs are rectorrhagia (66.0%). Endoscopy
(94.0% of patients) showed an ulcerative-budding appearance in 84.0% of cases.
The preferred location was the lower rectum 66.0%). The predominant histologic
type is adenocarcinoma lieberkunien (82.0%). Computed tomography is performed
in 78% of cases and MRI in 30%. Stage III accounts for 70.0% of cases.
Thirty-two patients (64.0%) were treated with conventional 2-beam 2D radiation
therapy with or without chemotherapy. The total dose of 46 Gy in 23 sessions
was the most used, found in 22 patients; 30 Gy in 10 sessions in 9 cases. And
16 Gy in 10 sessions, found in 1 case. Surgery performed was abdominoperineal
amputation (58.0%) and conservative surgery (42.0%). We note a complete
response in 28.0% of patients; 8.0%, an increase of 16.0% and a stabilization
of 4.0%. The sexual disorders are more important after radiotherapy compared to
non-irradiated patients: 31.3% vs 5.6% (p = 0.035). We observe respectively
that 2%, 6% and 8% of our patients had urinary disorders in the form of acute
retention, urinary incontinence, and urinary burning. Patient follow-up time
was between 0 and 42.83 months with an estimated average of 34.9 ± 3.37. The evolution is
marked at 6 months by a persistence of sexual disorders in 63.8% of cases and
urinary dysfunction in 4% of cases.