Das, J., Moquin, R.V., Dyckman, A.J., Li, T., Pitt, S., Zhang, R., Shen, D.R., McIntyre, K.W., Gillooly, K., Doweyko, A.M., Newitt, J.A., Sack, J.S., Zhang, H., Kiefer, S.E., Kish, K., McKinnon, M., Barrish, J.C., Dodd, J.H., Schieven, G.L. and Leftheris, K. (2010) 5-Amino-Pyrazoles as Potent and Selective p38α Inhibitors. Bioorganic & Medicinal Chemistry Letters, 20, 6886-6889.
https://doi.org/10.1016/j.bmcl.2010.10.034

has been cited by the following article:

• TITLE: A Mini-Review 5-Amino-N-Substituted Pyrazoles as Building Blocks for Bioactive Molecules

  AUTHORS: Wafa Bawazir

  KEYWORDS: Synthesis, 1, 5-Disubstituted Pyrazoles, Bioactive, Review

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.10 No.2, May 8, 2020

  ABSTRACT: In this review a five-membered heterocyclic ring having two adjacent nitrogen atoms known as Pyrazole, we have framed 5-amino-N-substituted pyrazoles in particular focusing on its substantial role as a building block and starting materials for producing enormous heterocyclic skeletons. The existence of this moiety in larger compounds renders them to expose medicinal, pharmacological and biological therapeutic activities. Enormous drugs contain 5-amino-N-substituted pyrazoles such as celecoxib anti-inflammatory, antipsychotic, anti-obesity, analgesic, and antidepressant. We reported various routes of synthesis and the use of these compounds.