Brian, V., Denoeud, L., Massougbodji, A., et al. (2008) Efficacy of Intermittent Treatment versus Chloroquine Prophylaxis to Prevent Malaria during Pregnancy in Benin. The Journal of Infectious Diseases, 198, 594-601.
ABSTRACT: Over 90 percent of illness and death attributable to malaria occurs in Sub-Saharan Africa, frequently among pregnant women and young children. Infection with P. falciparum results in high parasitemia percentages and it is the most frequent cause of malaria that results in illness and death in Africa. In areas with holoendemic transmission, such as in most of the Democratic Republic of the Congo (DRC), adults are exposed to malaria every few days or weeks throughout life and, if surviving, have relatively mild bouts of illness because of acquired immunity.