TITLE:
Study on the Corneal Higher-Order Aberrations and Correlation in Patients with Different Degrees of Myopia Suitable for Wavefront-Guided FS-LASIK
AUTHORS:
Chengzhe Wu, Xun Cui, Zhengri Li, Hong Cui, Lixia Sun, Haiyan Jin, Yingjun Li
KEYWORDS:
Corneal Refractive Surgery, Anterior Corneal Surface, Higher-Order Aberration, Spherical Aberration
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.8 No.1,
December
26,
2019
ABSTRACT: Background: Individualized corneal refractive surgery requires
an understanding of the basis of higher-order aberrations before surgery. To investigate the
characteristics and distribution of anterior surface wavefront aberrations in
patients suitable for corneal refractive surgery. Methods: A total of 121
myopic patients (121 eyes, 18 - 45 years old) who underwent corneal refractive
surgery were recruited from January to May 2016 at Affiliated Hospital, Yanbian
University. Patients were randomly selected by the Pentacam anterior segment
analysis system with a spherical equivalent (SE) of -0.25 to -10.00 D. The corneal anterior
aberrations (total higher-order aberration; spherical aberration; Coma;
Trefoil) and Q and K values were detected, and a correlation analysis of the
relevant parameters was carried out. Results: The root-mean-square
(RMS) of the third to sixth order aberrations of the corneal anterior wavefront
aberrations at a 6 mm analysis diameter showed a decreasing
trend in patients suitable for the corneal refractive surgery, and the RMS of
the third order aberrations accounted for 62.92% of the total HOAs. The coma
ratio (coma/total cornea higher-order aberrations) was
increased with the increasing diopters, while the spherical aberration ratio
(spherical aberration/total cornea higher-order aberrations) was not changed.
In addition, the spherical aberration was 0.203 ± 0.082 μm (range: 0.061 to
0.503 μm), and the Q30 was -0.19 ± 0.03
(range: -0.58 to 0.31). There were significant differences in the coma
aberrations of preoperative corneal anterior surface (3, 1) between the low, middle
and high myopia groups (P = 0.013).
The spherical equivalent was positively correlated with the corneal coma of the
anterior corneal surfaces (R =-0.241, P = 0.009), and the Q value was positively correlated with the total higher-order aberrations (R = 0.326, P Conclusions: Individual wavefront aberrations on the anterior
surfaces of the cornea are comparatively different, and the Zernike
coefficients are related to the degree of myopia. Spherical aberrations are the
most overriding aberrations of the cornea.