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has been cited by the following article:

• TITLE: Electroanalytical Investigation on Paracetamol on Boron-Doped Diamond Electrode by Voltammetry

  AUTHORS: Koffi Konan Martin, Lassine Ouattara

  KEYWORDS: Electroanalytical Method, Boron-Doped Diamond Electrode, Voltammetry, Paracetamol

  JOURNAL NAME: American Journal of Analytical Chemistry, Vol.10 No.11, November 18, 2019

  ABSTRACT: An electroanalytical method was developed for the direct quantitative determination of paracetamol in tablets based on its oxidation behavior. The electrochemical oxidation and determination of paracetamol were easily carried out on born-doped diamond (BDD) electrode using two voltammetric techniques (CV and DPV). The electrochemical measurements performed by cyclic voltammetric (CV) and differential pulse voltammetry (DPV) techniques were carried out using a cathodically pretreated boron-doped diamond electrode in HClO4 and KClO4 electrolytes. HClO4 was then selected for analytical purposes and scan rate studies were also completed. The oxidation of the paracetamol is found to be irreversible and a diffusion-controlled nature of the paracetamol oxidation peak was established. A linear calibration curve for DPV analysis was constructed in the paracetamol concentration range from 0 μM to 13.87 μM, with 0.16 μM and 0.55 μM as the detection and quantification limit respectively.