Article citationsMore>>
Maurinsh, Y., Schraml, J., De Winter, H., Blaton, N., Peeters, O., Lescrinier, E., Rozenski, J., Van Aerschot, A., De Clercq, E., Busson, R. and Herdewijn, P. (1997) Synthesis and Conformational Study of 3-Hydroxy-4 (Hydroxymethyl)-1-Cyclo- hexanyl Purines and Pyrimidines. The Journal of Organic Chemistry, 62, 2861-2871.
https://doi.org/10.1021/jo962204x
has been cited by the following article:
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TITLE:
Nucleosides 10: Synthesis of New Derivatives of Pyrimidine and Fused Pyrimidine Nucleosides of Expected Biological Activity
AUTHORS:
Laila M. Break, Mosselhi A. M. Mohamed, Ohoud A. A. Al-Thubaiti, Fatma E. M. Eibaih
KEYWORDS:
Synthesis, Nucleosides, Pyrimidines, Fused Pyrimidines Heterocycles, Biological Activity
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.9 No.3,
July
11,
2019
ABSTRACT: Pyrimidines, such as 6-amino-2-thio and 2-methylthiouracils and fused pyrimidines, such as thienopyrimidines reacted with 1-O-acetyl-2,3,5-tri-O- benzoyl-β-D-ribofuranose to get new derivatives of the corresponding nucleosides. The obtained protected nucleosides were deprotected by methanolic sodium methoxide to get the corresponding free uracil and thienopyrimidine nucleosides. The new nucleosides formed were tested for biological activity against some of microorganism (some fungi and bacteria species). Some of the tested products showed moderate activity and the results were reported.
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