TITLE:
Symplocosionosides A-C, Three Megastigmane Glycosides, a Neolignan Glucoside, and Symplocosins A and B, Two Triterpene Glycosyl Esters from the Leaves of Symplocos cochinchinensis var. Philippinensis
AUTHORS:
Wen-Hu Cai, Katsuyoshi Matsunami, Hideaki Otsuka, Yoshio Takeda
KEYWORDS:
Symplocos cochinchinensis var. Philippinensis, Symplocaceae, Megastigmane Glycoside, Neolignan Glucoside, Triterpene Glycosyl Ester, Modified Mosher’s Method
JOURNAL NAME:
American Journal of Plant Sciences,
Vol.2 No.4,
October
31,
2011
ABSTRACT: From the 1-BuOH-soluble fraction of a MeOH extract of the leaves of Symplocos cochinchinensis var. philippinensis, 12 compounds were isolated. Spectroscopic analyses of compounds 1 - 3 established their structures to be megastig-mane glycosides, named symplocosionosides A-C. The absolute structure of 1 was determined by the modified Mosher’s method. Compound 4 was found to be a neolignan glucoside and named symplocosneolignan. The structures of com-pounds 5 and 6, named symplocosins A and B, were elucidated to be the saponins of hederagenin sugar esters. The structures of the remaining known compounds (7 - 12) were identified by comparison of spectroscopic data with those reported in the literature.
