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Ryu, J.H., Lee, J.A., Kim, S., Shin, Y.A., Yang, J., Han, H.Y., Son, H.J., Kim, Y.H., Sa, J.H., Kim, J.-S., Lee, J., Lee, J. and Park, H.-G. (2016) Discovery of 2-((R)-4-(2-Fluoro-4-(methylsulfonyl)phenyl)-2-methylpiperazin-1-yl)-N-((1R,2s,3S,5S,7S)-5-hydroxyadamantan-2-yl)pyrimidine-4-carboxamide (SKI2852): A Highly Potent, Selective, and Orally Bioavailable Inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1). Journal of Medicinal Chemistry, 59, 10176-10189.
https://doi.org/10.1021/acs.jmedchem.6b01122

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