TITLE:
Gastric Gist as Cause of High Digestive Hemorrhage
AUTHORS:
Vinícius Moreira Paladino, Thiago Sande Miguel, Vinicius Sande Miguel, Marcia Machado Galvão Pereira, Fernando Antonio Galvão Pereira, Carolina Galvão Teixeira, Caroline Guida Babinski, Nayrton Kalys Cruz dos Anjos, Caio Marcus de Andrade Lopes, Daniel Almeida da Costa
KEYWORDS:
Gastrointestinal Stromal Tumor, Gastrointestinal Hemorrhage, Immunohistochemistry
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.7 No.1,
January
7,
2019
ABSTRACT: Introduction: Gastrointestinal stromal tumor (GIST) occurrence is uncommon and usually
manifested by nonspecific signs and symptoms, which hinders its reasoning as a
diagnostic hypothesis. The objective is to report a case of female GIST with
curative treatment through video-laparoscopy with partial gastrectomy. Case
report: A 61-year-old female patient attended the Luiz Gioseffi Jannuzzi
School Hospital (HELGJ) emergency room, with a sudden onset of upper
gastrointestinal bleeding with hemodynamic instability. After stabilization,
she was admitted for diagnostic investigation, showing sub-epithelial lesion of
antrum in upper digestive endoscopy (UDE) and solid-cystic mass in the gastric
antrum to computed tomography (CT). The conduct was the video laparoscopy
surgical approach with partial gastrectomy. The histopathological and
immunohistochemical aspects of the surgical specimen showed a gastrointestinal
stromal tumor (GIST) in a gastric antrum of low grade of malignancy, positive
e-Kit and mycotic index (50 cga) Discussion: Compared to the scarce reports in literature, the case described presented
typical epidemiology, but the clinical picture was not the most incident. Conclusions: Given the rarity of this pathology cases, it is essential to report these
in order to elucidate the specificities and also to discuss diagnostic and
therapeutic methods.