TITLE:
Cardiovascular Haemodynamics and Some Biochemical Profiles of Endotoxemic Buffalo Calves on Infusion of HSS, Flunixin Meglumine & Blood
AUTHORS:
J. P. Singh, D. V. Singh
KEYWORDS:
Shock, Endotoxemia, Buffalo Calves, Haemodynamics, Hypertonic Saline, Flunixin Meglumine, Blood
JOURNAL NAME:
Journal of Biomedical Science and Engineering,
Vol.11 No.6,
June
22,
2018
ABSTRACT: Six apparently healthy male buffalo calves aged between 6 months to one year with body weight range of 70 - 140 Kg were used in the present investigation. One animal was used for pilot trial for this group. Five calves were randomly taken into this group. The Eschrechia coli endotoxin infused i/v @5 mg/kg BW/hr for 3 hours to all the animals caused symptoms of restlessness, respiratory distress, snoring, diarrhea, profuse salivation along with the significant fall in systolic, diastolic, pulse and mean arterial venous pressure, hypoproteinemia at 1, 2 & 3 hour and hypoglycemia at 3rd hour i.e., end of endotoxin infusion. Respiration was increased significantly during endotoxin infusion at 2nd & 3rd hour and even afterwards till the end of the observation period i.e. 7 hrs. The treatment with hypertonic saline solution, flunixin meglumine and blood raised (p th, 6th & 7th hour respectively i.e., till the end of the observation period. There was no significant effect on Central Venous Pressure (CVP) and body temperature as measured from rectum.