TITLE:
Resistive Index for the Evaluation of Renal Damage in Diabetes Mellitus Type 2
AUTHORS:
Diyan Genov, Atanas Kundurdgiev, Ventsislava Pencheva
KEYWORDS:
Diabetes Mellitus Type 2, Resistive Index, Serum Creatinine, Proteinutia, Glomerular Filtration Rate
JOURNAL NAME:
Open Journal of Internal Medicine,
Vol.8 No.2,
June
21,
2018
ABSTRACT: Background: One of the most common causes of renal impairment and development of chronic kidney disease is diabetes mellitus type 2 (DM 2). The aim of this prospective study was to determine the role of Resistive Index (RI) as a non-invasive marker for the evaluation of renal impairment in patients with DM 2. Material and Methods: 47 patients with DM 2 in mean age 62.66 ± 10.081 years were included in the study for the period of one year. All of them were with well-compensated diabetes mellitus (HbA1c Results: Patients with RI 0.05 for all). There was significant difference between the groups according to serum creatinine (p = 0.026), GFR (p = 0.044) and the degree of proteinuria (p = 0.001). There was a positive correlation between RI and serum creatinine (r = 0.418; p = 0.001) and between RI and proteinuria (r = 0.396; p = 0.004). A negative correlation relationship between RI and GFR values was found (r = –0.413; p = 0.011). Conclusions: RI may be used as an indicator for the assessment of the severity of renal impairment in patients with DM 2. It correlates well with serum creatinine, GFR and proteinuria, which are proven biochemical parameters indicating the degree of renal damage in patients with DM 2.