TITLE:
Update on Gastric Cancer Epidemiology and Risk Factors
AUTHORS:
Nada Lahmidani, Mounia El Yousf, Nourdine Aqodad, Dafr Allah Benajah, Mohammed El Abkari, Adil Ibrahimi, Adil Najdi, Zineb Benbrahim, Naoufal Mellas
KEYWORDS:
Adenocarcinoma, Gastric, Incidence, Risk Factors, Helicobacter pylori
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.9 No.3,
March
14,
2018
ABSTRACT: Gastric adenocarcinoma is the most common gastric tumor.
It is the fifth most common cancer worldwide after lung cancer, breast, colo rectal
and prostate cancer. Long considered enigmatic, its epidemiology has changed over
time. In fact, the incidence of distal gastric cancer has declined while that of
the cardia was stable or increased. This cancer is multifactorial but reducing the
incidence of distal cancer is particularly attributed to advances in the treatment
of H. pylori infection. In this review,
we analyzed the available data concerning the changing epidemiology of gastric cancer
and the main risk factors. The incidence of distal cancer is definitely declining
due to the control of Helicobacter pylori infection. Proximal gastric cancer and cardia cancer is particularly due to smoking,
overweight.